쥐치아재식 모델에서 치주인대의 처리방법에 따른 치주조직의 치유와 치근흡수에 관한 연구
THE EFFECT OF TWO KINDS OF PERIODONTAL LIGAMENT MANAGEMENT UPON PERIODONTAL HEALING AND ROOT RESORPTION AFTER REPLANTATION IN RATS
권소란, 금기연, 이승종,
소속 상세정보
권소란 ( Kwon So-Ran ) - 연세대학교 치과대학 치과보존학교실
금기연 ( Kum Kee-Yeon ) - 연세대학교 치과대학 치과보존학교실
이승종 ( Lee Seung-Jong ) - 연세대학교 치과대학 치과보존학교실
KMID : 0362320000250030338
Abstract
The effect of bench drying or removal of the periodontal ligament with NaOCl upon periodontal healing and root resorption after replantation of molars was studied in rats. A total of 40 Sprague-Dawley female rats were used and fed a powdered purina rat chow diet containing 0.4% beta-aminoproprionitrile. The maxillary first molars were extracted and the periodontal ligaments were removed either by bench drying for 15 minutes or by immersion in 2.5% NaOCl solution. The rats were sacrificed at 5, 10, and 21 days by heart infusion. In order to observe the effect of 0.5% stannous fluoride, 10 ?4 M 10?4M , 10 ?2 M 10?2M , and 1M etidronate disodium on the early stage of periodontal healing, the periodontal ligament was removed with 2.5% NaOCl followed by immersion of the molar in the respective solutions for 5 minutes. The rats were sacrificed after 10 days and the following results were obtained. 1. The removal of the periodontal ligament with 2.5% NaOCl seemed to be more effective than bench drying, since the resorption area in the NaOCl treated group showed a gradual increase whereas a decline in resorption area from 5 days to 21 days was observed in the bench dried group. 2. The application of 0.5% stannous fluoride seemed to enhance the periodontal ligament attachment and active migration of fibroblasts could be observed. 3. The application of 10 ?4 M 10?4M , 10 ?2 M 10?2M , and 1M etidronate disodium led to a good periodontal ligament attachment. No evident areas of root resorption were found. 4. The use of β β -APN made it possible to extract the maxillary first molar with all five roots intact.
키워드
Periodontal ligament management; Periodontal healing; Root resorption; Beta-aminoproprionitrile; Stannous fluoride; Etidronate disodium
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